Paul Méfano (born in Iraq in 1937) is a french composer.

Paul Méfano studied at Paris Ecole Normale de Musique, and then pursued at Paris CRR - Conservatoire à Rayonnement Régional, where he was a student of Darius Milhaud. He completed his studies in Basel with Pierre Boulez, KarlHeinz Stockhausen, and Henri Pousseur an finally in Olivier Messiaen’s class at Paris CNSMDP - Conservatoire National Supérieur de Musique et de Danse de Paris.

In 1972 he founded the Ensemble 2E2M a group which he regularly conducts, and with which he has premiered more than five hundred works by young composers and with which he has made more than forty recordings. Amongst those younger composers are Stéphane de Gérando, Laurent Martin, Thierry Blondeau, Marc André, Michael Finissy, James Dillon, Bruce Mather, and Claude Lefèvre, but he has also championed older composers such as Jean Barraqué, Brian Ferneyhough, Franco Donatoni, Luigi Nono, Aldo Clementi, Philippe Boesmans, Morton Feldman, Edison Denisov, and John Cage, as well as participating in the rediscovery of Charles Valentin Alkan and the Czech composers who were interred at Terezienstadt in 1940. He is the founder of the Editions du Mordant for the publication of contemporary music, and of the Editions Musicales Européennes (dedicated primarily to young composers), and he has produced a number of notable radio series (Drake 2001).

In 1972 he was appointed director of the Conservatory of Champigny-sur-Marne, a duty which he performed until 1988. He also was professor of composition and orchestration at Paris CNSMD until 2002. One of his conducting students was the Canadian composer Claude Vivier.

From 1996 until 2005 he directed Versailles CRR - Conservatoire à rayonnement Régional .

Paul Mefano has been awarded the following prizes and honors : Chevalier de l'Ordre du Mérite (1980), Grand prix national de la Musique(1982), and Commandeur de l'Ordre des Arts et Lettres (1985).